Publications

Articles

69. Han S, Lee M, Shin Y, Giovanni R, Chakrabarty RP, Herrerias MM, Dada LA, Flozak AS, Reyfman PA, Khuder B, Reczek CR, Gao L, Lopez-Barneo J, Gottardi CJ, Budinger GRS, Chandel NS. 2023. Mitochondrial integrated stress response controls lung epithelial cell fate. Nature 620(7975):890-897.

68. Jin BR, Lim CY, Kim HJ, Lee M, An HJ. 2023. Antioxidant mitoquinone suppresses benign prostatic hyperplasia by regulating the AR-NLRP3 pathway. Redox Biol 65:102816.

67. Adhikari R, Jung J, Shiwakoti S, Park EY, Kim HJ, Ko JY, You J, Lee M, Oak MH. 2023. Capsaicin inhibits aortic valvular interstitial cell calcification via the redox-sensitive NFkappaB/AKT/ERK1/2 pathway. Biochem Pharmacol 212:115530. 

66. Kim HM, Kang YM, Jin BR, Lee H, Lee DS, Lee M, An HJ. 2023. Morus alba fruits attenuates atopic dermatitis symptoms and pathology in vivo and in vitro via the regulation of barrier function, immune response and pruritus. Phytomedicine 109:154579.

65. Kang YM, Kim HM, Lee M, An HJ. 2022. Effects of Echinocystic Acid on Atopic Dermatitis and Allergic Inflammation of the Skin and Lungs. Phytomedicine 104:154211. 

64. Choi JY, Kim H, Koo HY, You J, Yu DS, Lee YB, Lee M. 2022. Severe Scalp Psoriasis Microbiome Has Increased Biodiversity and Relative Abundance of Pseudomonas Compared to Mild Scalp Psoriasis. J Clin Med 11(23). 

63. Lee JO, Chu J, Jang G, Lee M, Chung YJ. 2022. tReasure: R-based GUI package analyzing tRNA expression profiles from small RNA sequencing data. BMC Bioinformatics 23(1):155. 

62. Lee SY, Lee M, Yu DS, Lee YB. 2022. Identification of genetic mutations of cutaneous squamous cell carcinoma using whole exome sequencing in non-Caucasian population. J Dermatol Sci 106(2):70-77. 

61. Lee HR, Lee GY, Kim EW, Kim HJ, Lee M, Humphries RK, Oh IH. 2022. Reversible switching of leukemic cells to a drug-resistant, stem-like subset via IL-4-mediated cross-talk with mesenchymal stroma. Haematologica 107(2):381-392. 

60. Park J, Lee JO, Lee M, Chung YJ. 2022. AS-CMC: a pan-cancer database of alternative splicing for molecular classification of cancer. Sci Rep 12(1):21074.

59. Kim YS, Lee M, Chung YJ. 2022. Two subtypes of cutaneous melanoma with distinct mutational signatures and clinico-genomic characteristics. Front Genet 13:987205. 

58. Lee M, Lee G, Kang HG, Suh JS. 2021. New susceptible locus, rs9428555, is associated with pediatric-onset immunoglobulin A nephropathy and immunoglobulin A vasculitis in Koreans. Genes Genomics 43(9):1049-1057.

57. Lee JO, Lee M, Chung YJ. 2021. DBtRend: A Web-Server of tRNA Expression Profiles from Small RNA Sequencing Data in Humans. Genes 12(10):1576.

56. Kang YM, Kim HM, Lee M, An HJ. 2021. Oleanolic Acid Alleviates Atopic Dermatitis-like Responses In Vivo and In Vitro. Int J Mol Sci 22(21):12000.

55. Kim HJ, Lee M, Lee YB, Yu DS. 2021. Investigation of Genetic Mutations in High-risk and Low-risk Basal Cell Carcinoma in a Non-Caucasian Population by Whole Exome Sequencing. Acta Derm Venereol 101(5):adv00458.

54. Chun SH, Kim EY, Yoon JS, Won HS, Yim K, Hwang HW, Hong SA, Lee M, Lee SL, Kim SS, Sun S, Ko YH. 2021. Prognostic value of noggin protein expression in patients with resected gastric cancer. BMC Cancer 21(1):558.

53. Choi E, Park SJ, Lee G, Yoon SK, Lee M, Lee SK. 2021. The GNAQ T96S Mutation Affects Cell Signaling and Enhances the Oncogenic Properties of Hepatocellular Carcinoma. Int J Mol Sci 22(6):3284.

52. Lee S, Nam M, Lee AR, Lee J, Woo J, Kang NS, Balupuri A, Lee M, Kim SY, Ro H, Choi YW, Kim DU, Hoe KL. 2021. Systematic Target Screening Revealed That Tif302 Could Be an Off-Target of the Antifungal Terbinafine in Fission Yeast. Biomol Ther 29(2):234-247.

51. Jin BR, Ju JY, Nugroho A, Lee M, An HJ. 2021. Carica papaya leaf extract inhibits prostatitis-associated prostatic hyperplasia via the TRAF6/TAK1/MEK/NF-kappaB pathway. Biomed Pharmacother 135:111197.

50. Jin BR, Chung KS, Hwang S, Hwang SN, Rhee KJ, Lee M, An HJ. 2021. Rosmarinic acid represses colitis-associated colon cancer: A pivotal involvement of the TLR4-mediated NF-kappaB-STAT3 axis. Neoplasia 23(6):561-573.

49. Kang YM, Lee M, An HJ. 2021. Oleanolic acid protects against mast cell-mediated allergic responses by suppressing Akt/NF-kappaB and STAT1 activation. Phytomedicine 80:153340.

48. Min K, Cho Y, Kim E, Lee M, Lee SR. 2021. Exogenous Glycine Betaine Application Improves Freezing Tolerance of Cabbage (Brassica oleracea L.) Leaves. Plants 10(12):2821 .

47. Lee S, Nam M, Lee AR, Baek ST, Kim MJ, Kim JS, Kong AH, Lee M, Lee SJ, Kim SY, Kim DU, Hoe KL. 2021. Knockdown of vps54 aggravates tamoxifen-induced cytotoxicity in fission yeast. Genomics Inform 19(4):e39.

46. Lee M, Yun S, Yu DS, Lee YB. 2021. Comparison of genetic mutations in squamous cell carcinoma and actinic keratosis of the forehead in the same patient using whole-genome sequencing. Eur J Dermatol 31(4):559-560.

45. Jin BR, Kim HJ, Sim SA, Lee M, An HJ. 2021. Anti-Obesity Drug Orlistat Alleviates Western-Diet-Driven Colitis-Associated Colon Cancer via Inhibition of STAT3 and NF-kappaB-Mediated Signaling. Cells 10(8):2060.

44. Jin BR, Lee M, An HJ. 2021. Nodakenin represses obesity and its complications via the inhibition of the VLDLR signalling pathway in vivo and in vitro. Cell Prolif 54(8):e13083.

43. Yin JH, Elumalai P, Kim SY, Zhang SZ, Shin S, Lee M, Chung YJ. 2021. TNNC1 knockout reverses metastatic potential of ovarian cancer cells by inactivating epithelial-mesenchymal transition and suppressing F-actin polymerization. Biochem Biophys Res Commun 547:44-51.

42. Lee G, Chung YJ, Lee M. 2021. Development of a Gene Expression Panel, for the Prediction of Protein Abundances in Cancer Cell Lines. Curr Bioinform 16(6):846-854.

41. Kang YM, Lee M, An HJ. 2021. New Potential of Roxatidine Acetate Hydrochloride on Atopic Dermatitis Mouse Model, Human Keratinocytes, and Human Skin Equivalent Model. Front Pharmacol 12:797086. 

40. Lee M, Lee G, Chung YJ, Kang MJ, Yu DS, Lee YB. 2020. A novel loci of the HR gene in Marie - Unna hereditary hypotrichosis using whole-exome sequencing. Indian J Dermatol Venereol Leprol 86(3):321-324.

39. Jin BR, Chung KS, Lee M, An HJ. 2020. High-Fat Diet Propelled AOM/DSS-Induced Colitis-Associated Colon Cancer Alleviated by Administration of Aster glehni via STAT3 Signaling Pathway. Biology 9(2):24.

38. Chung BY, Seo JM, Kang MJ, Lee M, Shin J, Chung YJ, Yu DS, Lee YB. 2020. The Assessment of Bacterial and Fungal Biodiversity in Korean Dermatomycoses Patients: A Pilot Study. J Mycol Infect 25(2):29-34.

37. Kim DU, Lee M, Han S, Nam M, Lee S, Lee J, Woo J, Kim D, Hoe KL. 2019. Optimization of a microarray for fission yeast. Genomics Inform 17(3):e28.

36. Lee M, Yoon J, Chung YJ, Lee SY, Choi JY, Shin OR, Park HY, Bahk WJ, Yu DS, Lee YB. 2018. Whole-exome sequencing reveals differences between nail apparatus melanoma and acral melanoma. J Am Acad Dermatol 79(3):559-561.e1.

35. Lee M, Kim K, Kim SY, Jung SH, Yoon J, Kim MS, Park HC, Jung ES, Chung YJ, Lee SH. 2018. Genomic structures of dysplastic nodule and concurrent hepatocellular carcinoma. Hum Pathol 81:37-46.

34. Song EH, Chung KS, Kang YM, Lee JH, Lee M, An HJ. 2018. Eupatilin suppresses the allergic inflammatory response in vitro and in vivo. Phytomedicine 42:1-8.

33. Lee M, Choi SJ, Han S, Nam M, Kim D, Kim DU, Hoe KL. 2018. Mutation Analysis of Synthetic DNA Barcodes in a Fission Yeast Gene Deletion Library by Sanger Sequencing. Genomics Inform 16(2):22-29.

32. Kang YM, Chung KS, Kook IH, Kook YB, Bae H, Lee M, An HJ. 2018. Inhibitory effects of bee venom on mast cell-mediated allergic inflammatory responses. Int J Mol Med 41(6):3717-3726.

31. Kim HS, Shin KJ, O J, Kwon HJ, Lee M, Yang HM. 2018. Stereotactic topography of the greater and third occipital nerves and its clinical implication. Sci Rep 8(1):870.

30. Lee AR, Lee SJ, Lee M, Nam M, Lee S, Choi J, Lee HJ, Kim DU, Hoe KL. 2018. Editor's Highlight: A Genome-wide Screening of Target Genes Against Silver Nanoparticles in Fission Yeast. Toxicol Sci 161(1):171-185.

29. Chung KS, Cheon SY, Roh SS, Lee M, An HJ. 2018. Chemopreventive Effect of Aster glehni on Inflammation-Induced Colorectal Carcinogenesis in Mice. Nutrients 10(2):202.

28. Yoon J, Chung YJ, Lee M. 2018. STADIUM: Species-Specific tRNA Adaptive Index Compendium. Genomics Inform 16(4):e28.

27. Lee M, Cho H, Jung SH, Yim SH, Cho SM, Chun JW, Paik SH, Park YE, Cheon DH, Lee JE, Choi JS, Kim DJ, Chung YJ. 2018. Circulating MicroRNA Expression Levels Associated With Internet Gaming Disorder. Front Psychiatry 9:81.

26. Jung SH, Lee SE, Lee M, Kim SH, Yim SH, Kim TW, Min CK, Chung YJ. 2017. Circulating microRNA expressions can predict the outcome of lenalidomide plus low-dose dexamethasone treatment in patients with refractory/relapsed multiple myeloma. Haematologica 102(11):e456-e459.

25. Lee M, Lee NY, Chung KS, Cheon SY, Lee KT, An HJ. 2017. Roxatidine attenuates mast cell-mediated allergic inflammation via inhibition of NF-kappaB and p38 MAPK activation. Sci Rep 7:41721.

24. Lee K, Lee M, Kim D. 2017. Utilizing random Forest QSAR models with optimized parameters for target identification and its application to target-fishing server. BMC Bioinformatics 18(Suppl 16):567.

23. Lee IW, Yoon J, Lee G, Lee M. 2017. Identification of New Potential APE1 Inhibitors by Pharmacophore Modeling and Molecular Docking. Genomics Inform 15(4):147-155.

22. Lee G, Lee M. 2017. Classification of Genes Based on Age-Related Differential Expression in Breast Cancer. Genomics Inform 15(4):156-161.

21. Jung SH, Kim CK, Lee G, Yoon J, Lee M. 2017. Structural Analysis of Recombinant Human Preproinsulins by Structure Prediction, Molecular Dynamics, and Protein-Protein Docking. Genomics Inform 15(4):142-146.

20. Jin BR, Chung KS, Cheon SY, Lee M, Hwang S, Noh Hwang S, Rhee KJ, An HJ. 2017. Rosmarinic acid suppresses colonic inflammation in dextran sulphate sodium (DSS)-induced mice via dual inhibition of NF-kappaB and STAT3 activation. Sci Rep 7:46252.

19. Kim JS, Rho S, Lee M, Kim S, Kim S, Hwang S. 2015. A case study of drug repositioning simulation based on distributed supercomputing technology. J KIISE 42(1):15-22.

18. Lee SH, Lee M, Kim HJ. 2014. Anatomy-based image processing analysis of the running pattern of the perioral artery for minimally invasive surgery. Br J Oral Maxillofac Surg 52(8):688-92.

17. Nam M, Lee SJ, Han S, Kim D, Lee M, Kang EJ, Park HO, Lee AR, Lee S, Kim CH, Kim DU, Hoe KL. 2014. Systematic targeted gene deletion using the gene-synthesis method in fission yeast. J Microbiol Methods 106:72-77.

16. Kim JS, Rho S, Lee M, Kim S, Kim S, Hwang S. 2014. Large-Scale Drug Repositioning Simulation based on HTCaaS. Proc KIISE:30-32.

15. Lee M, Park K, Kim D. 2013. Interaction network among functional drug groups. BMC Syst Biol 7(Suppl 3):S4.

14. Han S, Lee M, Chang H, Nam M, Park HO, Kwak YS, Ha HJ, Kim D, Hwang SO, Hoe KL, Kim DU. 2013. Construction of the first compendium of chemical-genetic profiles in the fission yeast Schizosaccharomyces pombe and comparative compendium approach. Biochem Biophys Res Commun 436(4):613-8.

13. Lee M, Han S, Chang H, Kwak YS, Weller DM, Kim D. 2013. FitSearch: a robust way to interpret a yeast fitness profile in terms of drug's mode-of-action. BMC Genomics 14(Suppl 1):S6.

12. Hong C, Lee M, Kim D, Kim D, Cho KH, Shin I. 2012. A checkpoints capturing timing-robust Boolean model of the budding yeast cell cycle regulatory network. BMC Syst Biol 6:129.

11. Lee J, Xia Y, Son MY, Jin G, Seol B, Kim MJ, Son MJ, Do M, Lee M, Kim D, Lee K, Cho YS. 2012. A novel small molecule facilitates the reprogramming of human somatic cells into a pluripotent state and supports the maintenance of an undifferentiated state of human pluripotent stem cells. Angew Chem Int Ed Engl 51(50):12509-13.

10. Lee M, Kim D. 2012. Large-scale reverse docking profiles and their applications. BMC Bioinformatics 13(Suppl 17):S6.

9. Kim DU, Hayles J, Kim D, Wood V, Park HO, Won M, Yoo HS, Duhig T, Nam M, Palmer G, Han S, Jeffery L, Baek ST, Lee H, Shim YS, Lee M, Kim L, Heo KS, Noh EJ, Lee AR, Jang YJ, Chung KS, Choi SJ, Park JY, Park Y, Kim HM, Park SK, Park HJ, Kang EJ, Kim HB, Kang HS, Park HM, Kim K, Song K, Song KB, Nurse P, Hoe KL. 2010. Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe. Nat Biotechnol 28(6):617-23.

8. Baek ST, Han S, Nam M, Kim YD, Kim L, Lee HJ, Heo KS, Lee H, Lee M, Park SK, Maeng PJ, Park Y, Lee S, Kim DU, Kim D, Hoe KL. 2008. Genome-wide identification of haploinsufficiency in fission yeast. J Microbiol Biotechnol 18(6):1059-63.

7. Baek ST, Kim DU, Han S, Woo IS, Nam M, Kim L, Heo KS, Lee H, Hwang HR, Choi SJ, Won M, Lee M, Park SK, Lee S, Kwon HJ, Maeng PJ, Park HM, Park Y, Kim D, Hoe KL. 2008. Genome-wide Drug-induced Haploinsufficient Screening of Fission Yeast for Identification of Hydrazinocurcumin Targets. J Microbiol Biotechnol 18(2):263-269.

6. Lee WC, Lee M, Jung JW, Kim KP, Kim D. 2008. SCUD: Saccharomyces cerevisiae ubiquitination database. BMC Genomics 9:440.

5. Lee M, Jeong CS, Kim D. 2007. Predicting and improving the protein sequence alignment quality by support vector regression. BMC Bioinformatics 8:471.

4. Kim K, Kim SY, Lee M, Yum MK. 2006. Hurst exponents in futures exchange markets. Int J Mod Phys C 17(12):1831-1838.

3. Lee M, Jeong CS, Kim D. 2006. A new method to predict the protein sequence alignment quality. Bioinform Biosyst 1(1):82-7.

2. Jeong CS, Lee M, Kim D. 2006. Detecting remote homolog by protein similarity network. IFMBE Proc 14:169-71.

1. Park J, Lee M, Bhak J. 2005. HExDB: Human EXon DataBase for Alternative Splicing Pattern Analysis. Genomics Inform 3(3):53-7.

Patents

9. Park SN, Lee M, Lee G; Catholic University of Korea Industry Academic Cooperation Foundation,  Dongguk University Industry-Academic Cooperation Foundation; SNP marker for chronic sensorineural tinnitus diagnosis and diagnosis method using the same; KR102481211B1 filed Aug 2020, and issued Dec 2022.

8.  Suh JS, Lee M, Kang HG; Catholic University of Korea Industry Academic Cooperation Foundation,  Dongguk University Industry-Academic Cooperation Foundation, Seoul National University Industry-Academic Cooperation; SNP markers for Immunoglobulin A (IgA) nephropathy and IgA vasculitis diagnosis and diagnosis method using the same; KR102409336B1 filed Aug 2020, and issued Jun 2022.

7.  Kim D, Lee K, Lee M; Korea Advanced Institute of Science and Technology, Catholic University of Korea Industry Academic Cooperation Foundation; Method of predicting multiple targets of drug utilizing random forest QSAR models; KR102228552B1 filed Oct 2018, and issued Mar 2021.

6. Chung YJ, Lee M, Lee JE, Park YE; Catholic University of Korea Industry Academic Cooperation Foundation, Korea Institute Of Science And Technology; Biomarker comprising Gamma-aminobutyric acid B receptor 2 for diagnosing internet gaming disorder and uses thereof; KR102072564B1 filed Jun 2018, and issued Jan 2020.

5. Chung YJ, Lee M, Lee JE, Park YE; Catholic University of Korea Industry Academic Cooperation Foundation, Korea Institute Of Science And Technology; Biomarker comprising dihydropyrimidinase-related protein 2 for diagnosing internet gaming disorder and uses thereof; KR102072563B1 filed Jun 2018, and issued Jan 2020.

4. Chung YJ, Lee M, Jung SH; Catholic University of Korea Industry Academic Cooperation Foundation; Composition for diagnosis of internet gaming disorder and method of providing information for diagnosis thereof ; KR102072562B1 filed Jun 2018, and issued Jan 2020.

3. Hoe KL, Kim DU, Kim D, Park HO, Nam M, Han S, Lee H, Lee M, Noh EJ, Lee AR; Korea Research Institute of Bioscience and Biotechnology; Method for preparation of deletion cassette using synthesis of gene comprising artificial sequences linkers; KR101067899B1 filed Oct 2008, and issued Sep 2011. 

2. Hoe KL, Kim DU, Won M, Yoo HS, Kim D, Park HO, Chung KS, Jang YJ, Nam M, Han S, Choi SJ, Baek ST, Kim HB, Heo KS, Lee H, Lee M, Park JY; Korea Research Institute of Bioscience and Biotechnology; Genome-wide construction of Schizosaccharomyces pombe heterozygous deletion mutants containing gene-specific barcodes by the methods of 4-round serial or block PCR, or total gene synthesis thereof; KR101098032B1 filed Apr 2008 and issued Dec 2011;  WO2009131279A1 published Oct 2009; CN102016022B issued May 2014; JP5608637B2 issued Oct 2014;  US9670480B2 issued Jun 2017. 

1.  Kim D, Jeong CS, Lee M; Korea Advanced Institute of Science and Technology; Apparatus for prediction of tertiary structure from the protein amino acid sequences and prediction method thereof; KR100836166B1 filed Jun  2006, and issued Aug 2008.